Laryngeal Carcinoma

A 58-year-old male smoker presents with hoarseness of voice for 3 months. Laryngoscopy reveals a 2 cm exophytic lesion on the left vocal cord with no evidence of distant metastases. Biopsy confirms squamous cell carcinoma. CT chest shows no involvement of anterior commissure or subglottis. What is the drug of choice for induction chemotherapy in this patient with locally advanced laryngeal carcinoma?

A 62-year-old male with a 40 pack-year smoking history presents with progressive dysphagia and a palpable left neck mass. Laryngoscopy shows a large lesion in the false vocal cord region. Which histopathological and clinical feature best distinguishes supraglottic squamous cell carcinoma from glottic squamous cell carcinoma?

Which laryngeal site accounts for the highest incidence of squamous cell carcinoma of the larynx?

A 58-year-old male smoker presents with progressive hoarseness for 3 months and dysphagia. Laryngoscopy reveals a white, irregular lesion on the left vocal cord. What is the investigation of choice to confirm the diagnosis of laryngeal carcinoma?

A 65-year-old male with stage IIB squamous cell carcinoma of the larynx (T2N1M0) is deemed suitable for organ preservation. After completing induction chemotherapy with cisplatin and 5-FU, he is to receive concurrent chemoradiation. What is the drug of choice for concurrent chemotherapy during radiotherapy?