Acute Inflammation MCQ — NEET PG Practice Question | NEETPGAI
Acute Inflammation
medium
microscope Pathology
Which histological feature best distinguishes acute suppurative inflammation from acute fibrinous inflammation?
A. Increased vascular permeability without cell infiltration
B. Presence of macrophages and lymphocytes
C. Fibrin deposition in vessel walls and tissue spaces
D. Predominance of neutrophils with abscess formation
Explanation
Distinguishing Acute Suppurative from Fibrinous Inflammation
Key Morphological Differences
Key Point
Acute suppurative inflammation is characterized by pus formation (dead neutrophils, bacteria, and tissue debris), while fibrinous inflammation features fibrin deposition as the dominant finding.
Comparison Table
Table
Feature
Suppurative Inflammation
Fibrinous Inflammation
Primary exudate
Purulent (pus)
Fibrin-rich
Dominant cell type
Neutrophils (PMNs)
Fibrin + neutrophils
Abscess formation
Yes (characteristic)
No
Tissue damage
Liquefactive necrosis
Fibrinoid necrosis
Common sites
Localized infections (boils, carbuncles)
Serosal surfaces (pericarditis, peritonitis)
Bacterial association
Pyogenic bacteria (S. aureus, Streptococcus)
Streptococcal infections, immune reactions
Pathological Basis
High-YieldNEET PG
Suppurative inflammation = abscess = localized collection of pus. The hallmark is neutrophil accumulation with liquefactive necrosis of tissue.
Clinical Pearl
A boil or carbuncle is the classic example of suppurative inflammation — you see a central core of dead neutrophils and bacteria (pus) surrounded by a wall of granulation tissue and fibroblasts.
Why Fibrinous Inflammation Is Different
Fibrinous inflammation occurs when:
Immune complexes deposit in vessel walls
Severe endothelial injury triggers coagulation cascade
Fibrin precipitates in tissue and vessel walls
Seen in acute rheumatic fever, acute glomerulonephritis, type III hypersensitivity reactions
