## Epiphyseal Fusion Timeline in Females **Key Point:** The medial (inner) condyle of the distal femur is one of the last epiphyses to fuse in females, closing at approximately **18–20 years of age**. ### Distal Femur Fusion Sequence The distal femur has two epiphyses: - **Lateral condyle**: fuses at 16–17 years - **Medial condyle**: fuses at 18–20 years (later) This is a critical landmark in forensic age determination because fusion of the medial condyle indicates the individual has likely reached early adulthood. ### Clinical Application **High-Yield:** In skeletal remains, the presence of an unfused medial condyle of the distal femur in females suggests age **< 18 years**, while fusion indicates age **≥ 18 years**. This distinction is crucial in cases of disputed age and criminal investigations involving young individuals. ### Sex Differences Females typically show epiphyseal fusion 1–2 years earlier than males. Males show fusion of the medial condyle at approximately **19–21 years**.
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