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Subjects/Medicine/AIIMS 2017
AIIMS 2017
medium
stethoscope Medicine

Asymptomatic hep B is common in 2-3% normal population, but there is increased risk of transmission into hepatocellular carcinoma. Why?

A. Inability to induce inflammation to remove the organism
B. High level of transaminases
C. High rate of proliferation of virus
D. Integration of viral DNA with host DNA

Explanation

Option A- Explanation for carrier stage Option C- Refers to high infectivity of the virus so basically higher chances of infection but not cancer. Option D- This leads to inhibition of apoptosis so might cause cancer of liver (HCC)

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