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Subjects/Pathology/AIIMS 2018
AIIMS 2018
medium
microscope Pathology

Immunofluorescence staining pattern from a kidney biopsy from a 35-year-old patient presenting with proteinuria has been shown below. What is the most probable cause?

A. FSGS
B. PSGN
C. Lupus Nephritis
D. Goodpasture syndrome

Explanation

FSGS- Focal segmental glomerulosclerosis is associated with focal involvement of kidneys and deposition of IgM,C3 ,C1q PSGN- It is an immunocomplex disease and granular pattern is observed on immunofluorescence. There is deposition of C3,C1q and IgG in granular pattern Goodpasture syndrome- Auto antibodies against basement membrane ,linear pattern on immunofluorescence Lupus Nephritis- seen in SLE.

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