Interpretation of common serological patterns in HBV infection Virus / Antibody markers Interpretation HBsAg HBeAg Anti - HBc Anti - HBs Anti - HBe + + IgM - - Acute HBV infection, highly infectious + + IgG - - Late/chronic HBV infection or carrier state: highly infectious + - IgG - +/- Late /chronic HBV infection or carrier state; low infectivity - +/- IgM - +/- Seen rarely in early acute HBV infection; infectious - - IgG +/- +/- Remote HBV infection; infectivity nil or very low - - - + - Immunity following HBV vaccine
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