Blocking voltage gated K+ channels on presynaptic membrane | K+ exit stops | Membrane does not get hyperpolarized |Continued Ach release When an AP depolarizes the presynaptic membrane=Ca++ channel open=allow release of neurotransmitter=from terminal=into synaptic cleft=forming bridge for the vesicles and release sites of a depolarized membrane. Blocking voltage gated Na++ channels will block the AP propagation Chloride channels are present=on the post synaptic membrane.
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