Shine Dalgarno sequence Only in prokaryotes present at -10 position on mRNA, Rich in purines. SD sequence is complementary to 16 s rRNA, Their binding helps in binding of mRNA with ribosome during initiation of translation * In eukaryotic cells, ribosomes recognize most eukaryotic mRNAs by binding to the 7-methylguanosine cap at their 5' terminus.
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