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Subjects/Anatomy/Anatomy
Anatomy
medium
bone Anatomy

In gene studies, the specific site to which the enzyme CRE recombinase binds is:

A. RE site
B. LoxP site
C. NT site
D. F site

Explanation

Ans: B. LoxP siteCre-Lox recombination - Known as "Site-specific recombinase technology".* Widely used to carry out deletions, inseions, translocations & inversions at specific sites in cellular DNA.* Consists of Cre-recombinase enzyme. - Recombines a pair of sho target sequences called "Lox sequences".* Cre enzyme & original Lox site - Referred as "LoxP sequence" - Derived from bacteriophage P1.* Lox P (locus of X-over P1) - Site on bacteriophage P1 consisting of 34 bp.Ref https://en.wikipedia.oig/wiki/Cre-Lox_recombination)

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