Ans: D. Penetration into the subarachnoid space(Ref: Miller 7/e p1895: Barash 5/e p1478, 2405)Penetration of drug into the subarachnoid space sholy causes cardiovascular symptoms like hypotension.Systemic absorption of drugs causes neurological symptoms before hypotension.Vasovagal shock occurs immediately, i.e. even before the needle for epidural anesthesia is injected.
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