A 62-year-old man with atrial fibrillation (CHA₂DS₂-VASc score = 4) presents to the emergency department with acute ischaemic stroke. CT head shows no haemorrhage. He is on aspirin 75 mg daily but was not on anticoagulation. Thrombolysis with intravenous alteplase is being considered. What is the most appropriate immediate next step regarding anticoagulation?

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