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    Subjects/Pathology/Apoptosis vs Necrosis
    Apoptosis vs Necrosis
    medium
    microscope Pathology

    A 58-year-old man with a 20-year history of heavy alcohol consumption presents to the emergency department with acute onset epigastric pain, vomiting, and elevated serum amylase (850 U/L). Abdominal ultrasound shows pancreatic edema and peripancreatic fluid collection. On histopathology of a pancreatic biopsy obtained during endoscopic ultrasound, acinar cells show loss of cell membrane integrity, cytoplasmic swelling, and inflammatory cell infiltration. What is the most appropriate immediate next step in management?

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