A 6-year-old boy presents with intense pruritus, lichenified plaques on flexural surfaces (antecubital and popliteal fossae), and a 3-year history of recurrent skin infections. Serum IgE is markedly elevated. His mother reports that emollients alone provide only temporary relief. What is the most appropriate next step in management?

See the options, answer & explanation

Sign in free to reveal the answer choices, the correct answer, the detailed explanation, and AI-powered insights for this question.