A 28-year-old woman with a 10-year history of atopic dermatitis presents with widespread erythema, edema, and oozing affecting >50% of body surface area. She has failed to respond to potent topical corticosteroids and narrowband UVB phototherapy over 8 weeks. Serum IgE is >2000 IU/mL. What is the most appropriate next step in management?

See the options, answer & explanation

Sign in free to reveal the answer choices, the correct answer, the detailed explanation, and AI-powered insights for this question.