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Subjects/Biochemistry/Biochemistry
Biochemistry
medium
flask-conical Biochemistry

All of the following are the reasons responsible for ketosis in a patient of Von Gierke's disease?

A. They have hypoglycemia
B. Have low blood sugar levels
C. Oxaloacetate is required for gluconeogenesis
D. Low fat mobilization

Explanation

Answer- D. Low fat mobilizationExcessive fatty acid mobilization (not the Low fat mobilization) from adipose tissues leads to ketosis in Von-Gierke's disease.Type I glycogen storage disorder, inherited as autosomal recessive, due to the deficiency of glucose-6 phosphatase.Excessive fatty acid mobilization from adipose tissues leads to ketosis.Deficiency of glucose-6 phosphatase leads to low blood sugar and hypoglycemic attacks.

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