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Subjects/Biochemistry/Biochemistry
Biochemistry
medium
flask-conical Biochemistry

In uncontrolled diabetes mellitus, elevated triglyceride and VLDL levels are seen due to:

A. Increased activity of lipoprotein lipase and decreased activity of hormone sensitive lipase
B. Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipase
C. Increase in peripheral LDL receptors
D. Increased activity of hepatic lipase

Explanation

Answer- B. Increased activity of hormone sensitive lipase and decreased activity of lipoprotein lipaseIn uncontrolled diabetes mellitus, elevated triglyceride and VLDL levels sre seen due to increased activity of hormone sensitive lipase (which insulin inhibits) and decreased activity of lipoprotein lipase (which insulin stimalates).

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