## Roper Hall Classification of Chemical Eye Injuries The Roper Hall classification system stratifies chemical eye injuries based on corneal clarity, limbal ischemia, and conjunctival involvement to predict visual prognosis. ### Roper Hall Grading System | Grade | Corneal Clarity | Limbal Ischemia | Conjunctival Involvement | Prognosis | |-------|-----------------|-----------------|--------------------------|----------| | **I** | Clear | None | None | Excellent | | **II** | Hazy, iris details visible | None | Involved but not total | Good | | **III** | Opaque, iris details obscured | <1/3 circumference | Total conjunctival involvement | Guarded | | **IV** | Opaque, white | ≥1/3 circumference | Total | Poor/Blind | **Key Point:** Grade III injuries show corneal opacity that obscures iris details (but not completely white) combined with limbal ischemia affecting less than one-third of the limbal circumference. **High-Yield:** Limbal stem cell damage is the critical prognostic factor in chemical injuries. Involvement of >50% of the limbal circumference (Grade IV) indicates irreversible damage and poor visual outcome. **Clinical Pearl:** In Grade III injuries, aggressive management including limbal stem cell transplantation may be considered if performed early, as some limbal stem cells remain viable. **Mnemonic:** **CLIC** — **Corneal** clarity, **Limbal** ischemia, **Iris** details, **Conjunctival** involvement (assess these four features in order to grade). 
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