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Subjects/Pathology/DIC
DIC
medium
microscope Pathology

Which of the following conditions is considered a common trigger or underlying cause for Disseminated Intravascular Coagulation (DIC)?

A. A. Chronic stable angina
B. B. Uncomplicated urinary tract infection
C. C. Acute promyelocytic leukemia (AML M3)
D. D. Mild allergic reaction

Explanation

Acute promyelocytic leukemia (AML M3) is notoriously associated with DIC due to the release of procoagulant substances from the abnormal promyelocytes. Other common triggers for DIC include severe sepsis, trauma, obstetric complications (e.g., placental abruption, amniotic fluid embolism), massive transfusions, and certain solid tumors. Chronic stable angina, uncomplicated urinary tract infection, and mild allergic reactions are generally not associated with DIC.

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