A 42-year-old woman on thiazide diuretics for hypertension presents with symptomatic hyponatremia (Na 122 mEq/L). She is euvolemic on examination. Serum osmolality is 250 mOsm/kg and urine osmolality is 580 mOsm/kg. Which investigation would best differentiate thiazide-induced hyponatremia from SIADH?
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