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    Subjects/Pathology/Endometrial Carcinoma
    Endometrial Carcinoma
    hard
    microscope Pathology

    A 58-year-old postmenopausal woman from Delhi presents with vaginal bleeding for 3 months. She has a BMI of 34 kg/m², hypertension on amlodipine, and type 2 diabetes mellitus. On examination, the uterus is normal size and non-tender. Transvaginal ultrasound shows an endometrial thickness of 18 mm with heterogeneous echotexture. Endometrial biopsy reveals a grade 2 adenocarcinoma with invasion into the inner half of the myometrium. Immunohistochemistry shows intact MLH1, MSH2, MSH6, and PMS2 expression. What is the most likely molecular subtype according to the TCGA classification?

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