A test with very high sensitivity (98%) means it correctly identifies almost all individuals who have the disease (few false negatives). Therefore, if a person tests negative with a highly sensitive test, it is very likely that they do not have the disease. This makes a highly sensitive test excellent for 'ruling out' a disease, especially in screening programs where the goal is to identify all potential cases for further investigation. Option A and C are incorrect because a moderate specificity (70%) means there will be a significant number of false positives (30% of healthy individuals will test positive). This makes it unsuitable for confirming a diagnosis or definitively identifying those with the disease without further confirmatory tests. Option D is incorrect; a moderate specificity of 70% implies a 30% false positive rate, meaning it will produce a relatively high number of false positive results, not reduce them.
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