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    Subjects/Physiology/Gastric Acid Secretion and Regulation
    Gastric Acid Secretion and Regulation
    hard
    heart-pulse Physiology

    A 52-year-old man with chronic peptic ulcer disease is found to have elevated fasting serum gastrin (>1000 pg/mL) and gastric pH < 2. Which feature best distinguishes Zollinger-Ellison syndrome (ZES) from simple antral G-cell hyperplasia?

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