A 58-year-old Indian male with a 10-year history of pernicious anemia presents with epigastric pain and weight loss. Endoscopy reveals a large ulcerated mass in the gastric cardia. Histology shows adenocarcinoma with extensive mucin production and signet-ring cells. Which single feature best distinguishes this diffuse-type gastric carcinoma from early gastric carcinoma (EGC)?

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