The Nottingham Histologic Grade (NHG), also known as the Elston-Ellis grade, for invasive breast carcinoma assesses three morphological features: the degree of tubule formation, nuclear pleomorphism (variation in nuclear size and shape), and mitotic count (number of mitotic figures per high-power field). Each feature is scored from 1 to 3, and the sum determines the overall grade (Grade I, II, or III). Lymph node status is a critical component of tumor staging (TNM system), which describes the anatomical extent of the disease, but it is not part of the histological grading system itself.
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