## Distinguishing Epidural from Subdural Hematoma ### Key Clinical Presentation Differences **Key Point:** The **lucid interval** is the hallmark discriminator of epidural hematoma. Patients typically lose consciousness at impact, regain consciousness and appear well (lucid interval lasting minutes to hours), then deteriorate rapidly as intracranial pressure rises. ### Pathophysiological Basis | Feature | Epidural Hematoma | Acute Subdural Hematoma | |---------|-------------------|------------------------| | **Bleeding source** | Meningeal artery (usually middle meningeal) | Bridging cortical veins | | **Location** | Between dura and skull | Between dura and brain surface | | **Typical CT appearance** | Lens-shaped (biconvex) | Crescent-shaped | | **Lucid interval** | Present in ~50% of cases (classic) | Rare; immediate deterioration typical | | **Onset of symptoms** | Often delayed (minutes to hours) | Usually immediate or very rapid | | **Prognosis** | Better if evacuated urgently | Worse; higher mortality | ### Clinical Pearl **High-Yield:** The lucid interval occurs because: 1. Initial impact causes brief loss of consciousness (concussion) 2. Arterial bleeding (epidural) is slower initially than venous bleeding 3. Patient wakes as brain swelling is still compensated 4. As hematoma expands, ICP rises exponentially → rapid deterioration In contrast, subdural hematoma from torn bridging veins causes immediate brain injury and swelling, with no lucid interval. ### Clinical Presentation Timeline ```mermaid flowchart TD A[Head Injury with LOC]:::outcome --> B{Type of bleeding?}:::decision B -->|Arterial - Epidural| C[Patient regains consciousness]:::action B -->|Venous - Subdural| D[Persistent altered consciousness]:::outcome C --> E[Lucid interval<br/>Patient appears well]:::action E --> F[Rapid deterioration<br/>Pupil dilation, hemiparesis]:::urgent D --> G[Immediate neurological decline<br/>or worsening]:::urgent F --> H[Emergency evacuation]:::action G --> H ``` **Mnemonic:** **EPIDURAL = LUCID** — Epidural = Lucid interval (classic presentation) [cite:Harrison 21e Ch 446] 
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