A hordeolum is an acute bacterial infection, usually staphylococcal, of the sebaceous glands of the eyelid. An external hordeolum (stye), as seen in the image, is an infection of the glands of Zeis or Moll, which are located at the eyelid margin. It presents as a painful, red, tender lump that often points to the skin surface, sometimes with a visible yellowish head (pustule) as depicted. An internal hordeolum is an infection of a Meibomian gland, located deeper within the tarsal plate.
| Feature | Hordeolum (Stye) | Chalazion | Blepharitis | Dacryocystitis |
|---|---|---|---|---|
| Location | Eyelid margin (Zeis/Moll glands) or tarsal plate (Meibomian) | Tarsal plate (Meibomian gland) | Eyelid margins (diffuse) | Medial canthus (lacrimal sac) |
| Onset | Acute | Chronic | Chronic/Recurrent | Acute/Chronic |
| Pain | Painful, tender | Painless (usually), non-tender | Itchy, burning, gritty sensation | Painful, tender |
| Appearance | Red, swollen, localized pustule/abscess | Firm, rubbery, non-tender nodule, deeper | Red, inflamed margins, crusting, scales | Red, swollen lump in medial canthus |
| Pathology | Acute bacterial infection (Staphylococcus) | Sterile granulomatous inflammation | Chronic inflammation of eyelid margins | Infection of lacrimal sac |
Kanski's Clinical Ophthalmology, 9th ed., Ch 4
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