livedo reticularis MCQ — NEET PG Practice Question | NEETPGAI
livedo reticularis
medium
stethoscope Medicine
A patient presents with the skin lesion shown in the image. The characteristic net-like, violaceous discoloration is most consistent with which of the following diagnoses?
A. Erythema nodosum
B. Livedo reticularis
C. Cellulitis
D. Urticaria
Explanation
Image Findings
A widespread, net-like (reticulated) pattern of bluish-red (violaceous) discoloration on the skin of a limb.
The discoloration forms irregular, branching, and interconnected rings or patches.
The central areas within the "net" appear relatively paler or normal skin colored.
No significant elevation, scaling, blistering, or ulceration is evident.
Diagnosis
Key Point
The image demonstrates a classic livedo reticularis, characterized by a persistent, reticulated, bluish-red vascular pattern on the skin.
Livedo reticularis is a common cutaneous manifestation resulting from impaired blood flow in the dermal capillaries and venules. This leads to deoxygenated blood pooling, creating the characteristic net-like, mottled appearance. It can be physiological (cutis marmorata, often transient with cold exposure) or pathological, associated with various underlying conditions affecting vascular integrity or blood viscosity.
Differential Diagnosis
Table
Feature
Livedo Reticularis
Erythema Nodosum
Urticaria
Cellulitis
Appearance
Net-like, violaceous, mottled vascular pattern
Tender, erythematous subcutaneous nodules
Transient, itchy wheals with central pallor
Diffuse, spreading erythema, warmth, swelling
Palpation
Non-palpable (unless associated with vasculitis)
Palpable, tender nodules
Palpable, raised wheals
Warm, tender, indurated
Distribution
Often limbs, trunk
Typically shins
Anywhere, often trunk and extremities
Anywhere, often lower extremities
Duration
Persistent or transient
Weeks to months
Hours (individual lesions)
Days to weeks
Clinical Relevance
Clinical Pearl
While often benign and physiological (especially in response to cold), persistent or extensive livedo reticularis, particularly if associated with ulceration or pain, warrants investigation for underlying systemic diseases such as autoimmune disorders (e.g., SLE, antiphospholipid syndrome), vasculitis, cryoglobulinemia, or hypercoagulable states.
High-Yield for NEET PG
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Livedo reticularis is a key dermatological sign that can indicate systemic disease, especially when it is fixed, painful, or associated with ulceration.
Key Point
The term "livedo racemosa" refers to a more irregular, broken, and widespread form of livedo reticularis, which is almost always pathological and often associated with vasculitis or thrombotic disorders.
Common Traps
Warning
Do not confuse physiological livedo reticularis (cutis marmorata) with pathological forms. Physiological livedo is transient and resolves with warming, whereas pathological forms are persistent and may be associated with other symptoms.
Reference
Robbins & Cotran Pathologic Basis of Disease, Ch 11; Harrison's Principles of Internal Medicine, Ch 62
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