A 6-month-old girl from Kerala presents with progressive irritability, seizures, developmental regression, and loss of previously acquired milestones over 3 months. On examination, she has a cherry-red spot on the macula, hepatosplenomegaly, and hypotonia. Serum sphingomyelinase activity is severely reduced. Bone marrow shows sea-blue histiocytes. What is the most likely diagnosis?
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