A 2-year-old girl from Tamil Nadu presents with progressive coarse facial features, corneal clouding, hepatosplenomegaly, and joint stiffness. Urine shows elevated heparan sulfate and dermatan sulfate. Enzyme assay shows deficiency of iduronate-2-sulfatase. What is the most appropriate next step in management?

See the options, answer & explanation

Sign in free to reveal the answer choices, the correct answer, the detailed explanation, and AI-powered insights for this question.