A 58-year-old man with a 40-pack-year smoking history presents with chronic cough and hemoptysis for 3 months. Chest X-ray reveals a left hilar mass. Bronchoscopy with biopsy shows replacement of normal ciliated columnar epithelium with stratified squamous epithelium in the bronchial mucosa, adjacent to which is a focus of disorganized epithelium with loss of maturation, increased nuclear-to-cytoplasmic ratio, and hyperchromatic nuclei. What is the relationship between the two histological findings observed in this patient?