A 22 years old male presented with history of fever, sore throat and enlarged neck lymph nodes. He was ordered a Paul-Bunnell test with a suspicion of Infectious mononucleosis. What is the immunological basis behind the use of this test?

Question

Accepted Answer

A. Heterophile antibody test. Answer- A. Heterophile antibody testEpstein-Bat virus (EBV) infection includes specific antibodies to EBV and various unrelated non-EBV heterophile antibodies. These heterophile antibodies reuct to antigens from animal RBCs. Sheep RBCs agglutinate in the presence of heterophile antibodies and are the basis for the Paul-Butrnell test.

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B. Complement mediated agglutination reaction

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C. Homophile antibody test

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D. Latex agglutination test

A 22 years old male presented with history of fever, sore throat and enlarged neck lymph nodes. He was ordered a Paul-Bunnell test with a suspicion of Infectious mononucleosis. What is the immunological basis behind the use of this test?

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A 22 years old male presented with history of fever, sore throat and enlarged neck lymph nodes. He was ordered a Paul-Bunnell test with a suspicion of Infectious mononucleosis. What is the immunological basis behind the use of this test?

Explanation

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