NEETPGAI
FeaturesBlogComparePricing
Log inStart Free
NEETPGAI

AI-powered NEET PG preparation platform. Master all 19 subjects with adaptive MCQs, AI tutoring, and spaced repetition.

Product

  • Features
  • Subjects
  • Previous Year Questions
  • Compare
  • Pricing
  • Blog

Features

  • Adaptive MCQ Practice
  • AI Tutor
  • Mock Tests
  • Spaced Repetition

Resources

  • Blog
  • Study Guides
  • NEET PG Updates
  • Contact & support

Legal

  • Privacy Policy
  • Terms of Service

Stay updated

© 2026 NEETPGAI. All rights reserved.
    Subjects/Surgery/Mirizzi Syndrome
    Mirizzi Syndrome
    medium
    scissors Surgery

    A 58-year-old woman presents with obstructive jaundice, right upper quadrant pain, and pruritus for 3 weeks. Ultrasound shows an impacted stone at the gallbladder neck with dilated intrahepatic bile ducts but a normal-caliber distal common bile duct. MRCP confirms a curvilinear indentation on the lateral wall of the common hepatic duct. The structure marked **A** in the diagram demonstrates the pathophysiology of this condition. Which of the following best describes the mechanism of jaundice in this patient?

    A. Intrinsic obstruction of the common bile duct by a freely mobile stone lodged at the ampulla of Vater
    B. Extrinsic compression of the common hepatic duct by an impacted cystic duct stone, causing high-level biliary obstruction proximal to the obstruction site
    C. Diffuse intrahepatic cholestasis secondary to multiple intrahepatic ductal stones with normal extrahepatic ducts
    D. Polypoid mass at the gallbladder fundus causing mechanical obstruction of the cystic duct lumen

    Explanation

    ## Why option 1 is right Mirizzi syndrome, as depicted at **A**, is defined by extrinsic compression of the common hepatic duct (CHD) by an impacted stone in the cystic duct or gallbladder neck (Hartmann pouch). This high-level obstruction produces obstructive jaundice with a characteristic imaging finding: dilated intrahepatic ducts with a normal-caliber distal CBD. The curvilinear indentation on the lateral CHD wall seen on ERCP is pathognomonic. The anchor fact—impacted gallstone causing external compression of the CHD—directly explains the patient's presentation (Csendes A et al., Br J Surg 1989). ## Why each distractor is wrong - **Option 2**: This describes choledocholithiasis (a stone within the CBD itself), not Mirizzi syndrome. In choledocholithiasis, the stone obstructs the CBD directly from within, not from external compression of the CHD. The imaging would show a dilated CBD distal to the stone, not a normal distal CBD. - **Option 3**: This describes intrahepatic cholestasis with multiple stones (as in diagram **C**), which would present with diffuse intrahepatic ductal dilatation. Mirizzi syndrome is a single impacted stone at the cystic duct/gallbladder neck causing localized external compression, not diffuse intrahepatic disease. - **Option 4**: This describes a polypoid gallbladder mass (diagram **D**) with no ductal involvement. Such lesions do not cause biliary obstruction or jaundice unless they occlude the cystic duct lumen itself, and they would not produce the characteristic curvilinear indentation or high-level CHD compression seen in Mirizzi syndrome. **High-Yield:** Mirizzi syndrome = impacted cystic duct stone → extrinsic CHD compression → proximal biliary dilatation with normal distal CBD (the hallmark imaging finding that distinguishes it from choledocholithiasis). [cite: Csendes A et al. Mirizzi syndrome and cholecystobiliary fistula classification. Br J Surg 1989]

    Practice similar questions

    Sign up free to access AI-powered MCQ practice with detailed explanations and adaptive learning.

    Start Practicing Free More Surgery Questions