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Subjects/OBG/OBG
OBG
medium
baby OBG

Estrogen and progesterone in the first 2 months pregnancy are produced by:

A. Fetal ovaries
B. Fetal adrenal
C. Placenta
D. Corpus luteum

Explanation

Ans: D. Corpus luteum(Ref Williams 24/e p169; Ganong 25/e p412, 24/e p414).Estrogen and progesterone in first 2 months of pregnancy - Produced by Corpus luteum.Functions of corpus luteum:Enlarged corpus luteum of pregnancy secretes estrogens, progesterone & relaxin.Progesterone & relaxin -Helps maintain pregnancy.By inhibiting myometrial contractions.Progesterone prevents prostaglandin production by uterus - Stops contractions.Corpus luteum function begins to decline after 8 weeks of pregnancy.Yet persists throughout pregnancy.In humans placenta produces sufficient estrogen & progesterone from maternal & fetal precursor taking over corpus luteum function after 6th week of pregnancy.Ovariectomy before 6th week a Hence cause aboion.Ovariectomy after 6th week doesn't affect pregnancy.Note:hCG secretion decreases after initial marked rise.Estrogen & progesterone secretion increase until just before paurition.

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