Ans. B. Replace warfarin with heparin in First trimesterRef: Williams Obstetrics, 24'h ed.Warf'arin has a low molecular weight and readily crosses the placenta.Exposure between the 6th and 9th weeks may result in warfarin embryopathy characterized by stippling of the veebrae and femoral epiphyses and by nasal hypoplasia with depression ofthe nasal bone.
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