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Subjects/OBG/OBG
OBG
medium
baby OBG

What dose of misoprostol is used orally to control bleeding in post paum hemorrhage?

A. 400 micrograms
B. 600 micrograms
C. 800 micrograms
D. 1000 micrograms

Explanation

Ans: B. 600 micrograms(Ref Williams 24/e 1785)Approved dose of misoprostol in emergent management of postpaum hemorrhage = 600 pg.Misoprostol (Cytotec):Synthetic prostaglandin E1 analogue.Effective in prevention & treatment of atony & postpaum hemorrhage.Derman (2006) compared a 600 ug oral dose given at delivery against placebo and found that the drug decreased hemorrhage incidence from 12 to 6 percent and that of severe hemorrhage from 1.2 to 0.2 percent.

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