In patients of PCOS: Alterations in gonadotropin releasing hromone pulsatality leads to preferential production of LH, as compared to FSH. Also estrogen has a positive feedback on LH and negative feedback on FSH which leads to increase in LH and decrease in FSH such that LH/FSH is > 2.1. Now the question arises whether this increase in LH is persistent. Most of the books do not state anything clearly except that there is an increase in the LH pulse amplitude and frequency. So I had to look up in Leon Speroff (which is the BAAP of all problems related to endocrinology and infertility in Gynae).
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