A 38-year-old woman with chronic mountain sickness presents with dyspnea and cyanosis. Her arterial blood gas shows pH 7.32, PaCO₂ 32 mmHg, PaO₂ 55 mmHg, and HCO₃⁻ 18 mEq/L. Clinical examination reveals polycythemia. Which investigation would best demonstrate the pathophysiological shift in her oxygen dissociation curve?

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