A 62-year-old man with chronic obstructive pulmonary disease (COPD) is admitted with acute exacerbation. Arterial blood gas shows pH 7.28 (acidosis), PaCO₂ 65 mmHg, and PaO₂ 55 mmHg. Regarding the factors affecting his oxygen dissociation curve in this clinical scenario, all of the following will shift the curve to the RIGHT and enhance oxygen unloading EXCEPT:
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