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Subjects/Pathology/Pathology
Pathology
medium
microscope Pathology

Insulin resistance is seen in liver disease because of-

A. Decreased secretion of insulin
B. Hepatic steatosis
C. Hepatocytedysfunction
D. Low 'C'peptide level

Explanation

Ans. b. Hepatic steatosis (Ref Robbins 9/e p842, 845, 8/e p 1136, http://wwwnews-medical.net/health/What-is-InsulinResistance.aspx )'Insulin resistance may also be caused by the damage of liver cells having undergone a defect of insulin receptors in hepatocytes.''Nonalcoholic fatty liver disease (NAFLD) refers to the presence of hepatic steetosis when no other causes for secondary hepatic fat accumulation (eg. heavy alcohol consumption) are present.

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