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Subjects/Pathology/Pathology
Pathology
medium
microscope Pathology

Gene which inhibits cell cycle is -

A. p53
B. RB
C. p16
D. Notch receptor

Explanation

Answer-A. p53Cell cycle inhibitorsCIP/KIP family - p21, p27, p57INK4a/ARF family - p161 NK4a, pl4ARFA G1 arrest can result simply by the p53 induced expression of p21 WAF1/CIP1/Sdi1 P53 also down regulates the expression of cyclin A, providing a secondary break on cell cycle progression into the through the S phase.

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