Platelet activation: The adherent platelets get activated, undergo a shape change and degranulate. The granules in the platelets can be Alpha granules having P-selectin, fibrinogen, fibronectin, factors V and VIII, platelet factor 4, platelet-derived growth factor, and transforming growth factor-β. Delta granules or delta bodies having ADP, ATP, ionized calcium, histamine, serotonin, and epinephrine.
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