A 38-year-old woman from rural Maharashtra presents with progressive fatigue, dyspnea on exertion, and jaundice for 3 weeks. On examination, she has pallor, icterus, and mild splenomegaly. Laboratory findings: Hb 7.2 g/dL, reticulocyte count 8%, total bilirubin 4.8 mg/dL (indirect 4.2 mg/dL), LDH 890 U/L, haptoglobin <10 mg/dL. Peripheral blood smear shows spherocytes, polychromasia, and occasional nucleated RBCs. What is the most appropriate next step in management?