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    Subjects/Surgery/Prostate Cancer
    Prostate Cancer
    medium
    scissors Surgery

    A 68-year-old man from rural Maharashtra presents with lower urinary tract symptoms (LUTS) for 6 months—nocturia (×4), weak stream, and incomplete emptying. Digital rectal examination reveals a hard, irregular, nodular prostate with loss of the median sulcus. PSA is 12.5 ng/mL (normal <4). Transrectal ultrasound-guided biopsy of the right lobe shows adenocarcinoma with a Gleason score of 7 (3+4). Staging CT abdomen/pelvis and bone scan are normal. What is the most appropriate next step in management?

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