A 68-year-old man from rural Maharashtra presents with lower urinary tract symptoms and a PSA level of 8.2 ng/mL. Digital rectal examination reveals a firm, nodular prostate. Transrectal ultrasound-guided biopsy shows adenocarcinoma with a Gleason score of 7 (3+4). Regarding prostate adenocarcinoma, all of the following are true EXCEPT:

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