The hallmark histopathological feature of a pterygium is elastotic degeneration (also known as basophilic degeneration or solar elastosis) of the subepithelial collagen, often accompanied by disruption or fragmentation of Bowman's layer at the leading edge of the corneal involvement. There is also overlying conjunctival epithelial hyperplasia and chronic inflammatory cell infiltration. Granulomatous inflammation is seen in conditions like sarcoidosis or foreign body reactions, amyloid deposition in amyloidosis, and lipid deposition in conditions like arcus senilis or corneal dystrophies.
Sign up free to access AI-powered MCQ practice with detailed explanations and adaptive learning.