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    Subjects/Anatomy/Radial Nerve — Course and Lesions
    Radial Nerve — Course and Lesions
    hard
    bone Anatomy

    A 32-year-old male presents with a stab wound to the mid-arm that damages the radial nerve as it exits the spiral groove. On examination, all of the following clinical findings are expected EXCEPT:

    A. Preserved ability to pronate the forearm
    B. Loss of sensation over the dorsal aspect of the first web space (between thumb and index finger)
    C. Loss of wrist extension (wrist drop)
    D. Loss of flexion at the interphalangeal joint of the thumb

    Explanation

    ## Radial Nerve Injury: Clinical Presentation ### Anatomical Context **Key Point:** A mid-arm radial nerve injury (at or distal to the spiral groove) results in loss of all radial nerve motor and sensory functions distal to the lesion. ### Expected Clinical Findings After Radial Nerve Injury | Finding | Mechanism | Status in This Case | |---|---|---| | **Wrist drop** | Loss of ECRL, ECRB, ECU → inability to extend wrist | ✓ LOST | | **Thumb extension loss** | Loss of EPB, EIP → cannot extend IP joint of thumb | ✓ LOST | | **Forearm pronation** | Pronator teres (median/AIN) and pronator quadratus (AIN) intact | ✓ PRESERVED | | **Dorsal 1st web space sensation** | Superficial radial nerve (sensory branch) | ✓ LOST | | **Thumb IP flexion** | Flexor pollicis longus (AIN — median nerve) | ✓ PRESERVED | ### Why Option 3 is CORRECT (the exception) **High-Yield:** Flexion at the interphalangeal (IP) joint of the thumb is performed by the **flexor pollicis longus (FPL)**, which is innervated by the **anterior interosseous nerve (AIN)**, a branch of the **median nerve**—not the radial nerve. Therefore, IP flexion of the thumb is **preserved** after radial nerve injury. **Clinical Pearl:** Students often confuse thumb extension (radial nerve → EPB, EIP) with thumb flexion (median nerve → FPL). A radial nerve injury causes loss of thumb extension but preserves thumb flexion. ### Verification of Other Options 1. **Option 0 (Expected):** Wrist extension is lost due to paralysis of ECRL, ECRB, and ECU. 2. **Option 1 (Expected):** Pronation is preserved because both pronator muscles (pronator teres and pronator quadratus) are innervated by the median nerve (AIN). 3. **Option 2 (Expected):** Sensory loss over the dorsal 1st web space occurs because the superficial radial nerve (terminal sensory branch) is damaged. ## Mnemonic: **LOAF** and Thumb Movements **LOAF** (Median nerve — lateral 3.5 fingers): - **L**umbrical (digits 1–2) - **O**pponens pollicis - **A**bductor pollicis brevis - **F**lexor pollicis brevis **FPL** (Anterior interosseous nerve — median) = Flexor pollicis longus (thumb IP flexion). **EPB + EIP** (Radial nerve) = Thumb extension.

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