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    Subjects/Anatomy/Radial Nerve — Course and Lesions
    Radial Nerve — Course and Lesions
    medium
    bone Anatomy

    A 32-year-old man presents with wrist drop and inability to extend the thumb after a fracture of the mid-shaft of the humerus. Which is the most common site of radial nerve injury in such fractures?

    A. Distal third of the arm near the elbow
    B. Radial groove (spiral groove) of the humerus
    C. Axilla
    D. Forearm at the level of the supinator muscle

    Explanation

    Most Common Site of Radial Nerve Injury in Humeral Fractures

    Anatomical Basis
    Key Point
    The radial nerve runs in the radial groove (spiral groove) on the posterior surface of the mid-shaft of the humerus, making this the most vulnerable site during mid-shaft humeral fractures.

    The radial nerve follows a predictable course:

    1. 1.
      Exits the axilla posteriorly
    2. 2.
      Enters the radial groove at the junction of proximal and middle thirds
    3. 3.
      Travels in the groove between the medial and lateral heads of triceps
    4. 4.
      Pierces the lateral intermuscular septum in the distal third
    5. 5.
      Emerges anterior to the lateral epicondyle
    Incidence of Radial Nerve Injury by Fracture Location
    Table
    Fracture SiteIncidence of RN InjuryMechanism
    Mid-shaft (radial groove)10–18%Direct trauma, angulation, traction
    Proximal third2–3%Rare, nerve already exited groove
    Distal third<5%Nerve already anteriorly displaced
    SupracondylarUncommonNerve protected by anterior displacement
    Clinical Presentation of Radial Nerve Palsy
    High-YieldNEET PG
    The classic triad of radial nerve injury:
    1. 1.
      Wrist drop — loss of extensor carpi radialis longus and brevis
    2. 2.
      Thumb extension loss — extensor pollicis longus paralysis
    3. 3.
      Finger extension loss — extensor digitorum paralysis
    Clinical Pearl
    Sensation loss over the dorsal first web space (between thumb and index finger) is a key sensory finding.
    Why the Radial Groove is Most Vulnerable
    Mnemonic
    GROOVE = Great vulnerability, Radial nerve tethered, Oscillating fracture edges, Osseous trauma, Vascular compromise, Excoriation
    • The nerve is tethered within the groove with limited mobility
    • Fracture fragments can directly lacerate or compress the nerve
    • Angulation and displacement cause traction injury
    • The nerve's intimate relationship with bone makes it susceptible to ischemia from vascular injury
    Prognosis
    Key Point
    Most radial nerve injuries from humeral fractures are neurapraxia or axonotmesis (not complete transection), with 90% recovering spontaneously within 3–4 months with conservative management.

    Standring Anatomy 42e Ch 48

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