For new smear-positive pulmonary TB cases (Category I) under RNTCP, the standard treatment regimen was 6 months. This consisted of an intensive phase of 2 months with HRZE (Isoniazid, Rifampicin, Pyrazinamide, Ethambutol) followed by a continuation phase of 4 months with HRE (Isoniazid, Rifampicin, Ethambutol). This regimen was typically administered intermittently (thrice weekly) in the RNTCP era, before the shift to daily regimens under NTEP.
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