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    Subjects/Psychiatry/Schizophrenia — Clinical Features
    Schizophrenia — Clinical Features
    hard
    brain Psychiatry

    A 28-year-old woman from Bangalore is brought to the emergency department by her husband after he found her standing motionless in the kitchen for 2 hours, unresponsive to his calls. When examined, she exhibits waxy flexibility of her limbs and does not speak spontaneously, though she follows simple commands inconsistently. Her husband reports a 3-month history of progressive social withdrawal, bizarre beliefs that her neighbors are poisoning her food, and episodes of talking to herself. He denies any recent fever, head trauma, or medication changes. Vital signs are stable; general physical and neurological examination are otherwise unremarkable. Which psychotic feature is most prominently demonstrated in this presentation?

    A. Disorganized behavior with flight of ideas
    B. Negative symptoms with catatonic features
    C. Positive symptoms with formal thought disorder
    D. Affective flattening with perseveration

    Explanation

    ## Catatonic Features in Schizophrenia **Key Point:** Catatonia is a psychomotor syndrome characterized by waxy flexibility, mutism, negativism, and posturing. While historically associated with catatonic schizophrenia, it now appears in only 5–10% of schizophrenia cases but remains a recognized specifier [cite:DSM-5]. ### Clinical Features Demonstrated **Catatonic manifestations present:** - **Waxy flexibility:** Limbs maintain imposed postures (hallmark sign) - **Mutism:** Lack of spontaneous speech despite intact comprehension - **Immobility:** Standing motionless for prolonged periods - **Inconsistent command following:** Suggests preserved cognition but motor inhibition **Negative symptoms context:** - Social withdrawal (3-month prodrome) - Reduced speech output (mutism) - Lack of spontaneous behavior **Positive symptoms (background):** - Delusions of poisoning - Auditory hallucinations (talking to herself) ### Why This Is "Negative Symptoms with Catatonic Features" ```mermaid flowchart TD A[Schizophrenia with Catatonia]:::outcome --> B[Positive Symptoms Present?]:::decision B -->|Yes| C[Delusions + Hallucinations]:::action A --> D[Negative Symptoms Present?]:::decision D -->|Yes| E[Withdrawal + Mutism + Reduced Spontaneity]:::action A --> F[Catatonic Features?]:::decision F -->|Yes| G[Waxy Flexibility + Immobility]:::action G --> H[Catatonic Specifier Applied]:::outcome ``` **High-Yield:** The question asks which feature is **most prominently demonstrated** — the waxy flexibility and mutism are the most striking clinical signs on examination, making catatonic features the primary focus, even though positive symptoms (delusions, hallucinations) are also present. **Clinical Pearl:** Catatonic schizophrenia often requires urgent medical workup to exclude medical causes (neuroleptic malignant syndrome, encephalitis, metabolic derangement) before attributing symptoms to primary psychiatric illness.

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