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    Subjects/Psychiatry/Serotonin Syndrome and NMS
    Serotonin Syndrome and NMS
    medium
    brain Psychiatry

    A 32-year-old woman with major depressive disorder on sertraline 100 mg daily presents to the emergency department with agitation, tremor, hyperreflexia, and a core temperature of 38.5°C. She admits to starting phenelzine (an MAOI) 2 days ago on her own after reading about it online. Vital signs show BP 148/92 mmHg, HR 112/min, RR 22/min. What is the most appropriate immediate next step in management?

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